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Interested in phage therapy? @TWINCORE is hosting a mini-symposium on these “microbe eaters” and their role in infection research and medicine on November 13. Speakers include #HIRI group leader Jens Hör and Milan Gerovac, a former postdoc in the Vogel lab and now a group leader at @Helmholtz_HZI. Guests are welcome, and registration is not required! Learn more: twincore.de/en/events/news-det

TWINCOREMini Symposium Phage Therapy

Laboratories provide controlled environments for experiments and measurements, fostering numerous inventions and discoveries. 🧪🧫 At the #HIRI, lab and infrastructure manager Christiane Albert-Weißenberger ensures that research in the lab runs smoothly.

In this interview, she talks about her work and responsibilities, the most exciting spot in the lab, and what the laboratories of the future might look like: helmholtz-hiri.de/en/newsroom/

The antimicrobial potential of #CRISPRCas systems is promising, yet how to best design or implement CRISPR nucleases remains poorly understood. An international team led by the #HIRI has now addressed this knowledge gap. The researchers conducted the first systematic interrogation of CRISPR antimicrobials using multidrug-resistant and hypervirulent bacteria as case studies, revealing wide variations in efficacy. Their findings were published in Nucleic Acids Research.
helmholtz-hiri.de/en/newsroom/

Helmholtz Institute for RNA-based Infection ResearchAntimicrobial agents of the futureHIRI researchers conducted the first systematic study of CRISPR-based antibiotics in Klebsiella pneumoniae

The World Antimicrobial Resistance Awareness Week (#WAAW) starts tomorrow, but at the #HIRI, the battle against #AntibioticResistance is a year-round task. 🦠 We are searching for new targets in various germs, as conventional antibiotics are becoming increasingly ineffective: helmholtz-hiri.de/en/newsroom/

One promising solution are programmable antibiotics, ASOs, studied by the laboratory of HIRI Director Jörg Vogel. They target #mRNAs needed by bacteria to synthesize new proteins & replicate. 🧬

Here comes our #introduction:

We are the Helmholtz Institute for RNA-based Infection Research, #HIRI for short, and are part of the #Helmholtz @association. We combine ribonucleic acid (#RNA) research with #infection #biology.

Based on novel findings from our strong basic #research program, our long-term goal is to develop innovative therapeutic approaches to better diagnose and treat human infections.

Find more information about us here: helmholtz-hiri.de/en