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UK<p><a href="https://www.europesays.com/uk/171894/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="">europesays.com/uk/171894/</span><span class="invisible"></span></a> Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer <a href="https://pubeurope.com/tags/Cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cancer</span></a> <a href="https://pubeurope.com/tags/carcinoma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>carcinoma</span></a> <a href="https://pubeurope.com/tags/Cell" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cell</span></a> <a href="https://pubeurope.com/tags/FallopianTube" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FallopianTube</span></a> <a href="https://pubeurope.com/tags/Gene" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Gene</span></a> <a href="https://pubeurope.com/tags/Genes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genes</span></a> <a href="https://pubeurope.com/tags/Genetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genetic</span></a> <a href="https://pubeurope.com/tags/Genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genetics</span></a> <a href="https://pubeurope.com/tags/Medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medicine</span></a> <a href="https://pubeurope.com/tags/MouseModel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MouseModel</span></a> <a href="https://pubeurope.com/tags/OrganicChemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OrganicChemistry</span></a> <a href="https://pubeurope.com/tags/OvarianCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OvarianCancer</span></a> <a href="https://pubeurope.com/tags/Ovaries" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Ovaries</span></a> <a href="https://pubeurope.com/tags/Pathology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pathology</span></a> <a href="https://pubeurope.com/tags/Prostate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Prostate</span></a> <a href="https://pubeurope.com/tags/ProstateCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ProstateCancer</span></a> <a href="https://pubeurope.com/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Research</span></a> <a href="https://pubeurope.com/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Science</span></a> <a href="https://pubeurope.com/tags/Tumor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tumor</span></a> <a href="https://pubeurope.com/tags/UK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UK</span></a> <a href="https://pubeurope.com/tags/UnitedKingdom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UnitedKingdom</span></a></p>
Fabrizio Musacchio<p>Our new <a href="https://sigmoid.social/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>preprint</span></a> on <a href="https://sigmoid.social/tags/ThreePhoton" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ThreePhoton</span></a> in vivo <a href="https://sigmoid.social/tags/imaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>imaging</span></a> of <a href="https://sigmoid.social/tags/neurons" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>neurons</span></a> and <a href="https://sigmoid.social/tags/glia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>glia</span></a> 🔬 in the medial prefrontal cortex (<a href="https://sigmoid.social/tags/mPFC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mPFC</span></a>) 🧠 with sub-cellular resolution 🔍 is out! Check it out on <a href="https://sigmoid.social/tags/biorxiv" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>biorxiv</span></a>:</p><p>🌍 <a href="https://www.biorxiv.org/content/10.1101/2024.08.28.610026v1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.08.28.610026v1</span></a></p><p><a href="https://sigmoid.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Neuroscience</span></a> <a href="https://sigmoid.social/tags/multiphoton" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>multiphoton</span></a> <a href="https://sigmoid.social/tags/3p" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>3p</span></a> vs. <a href="https://sigmoid.social/tags/2p" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>2p</span></a> <a href="https://sigmoid.social/tags/twophoton" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>twophoton</span></a> <a href="https://sigmoid.social/tags/hippocampus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>hippocampus</span></a> <a href="https://sigmoid.social/tags/drosophila" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>drosophila</span></a> <a href="https://sigmoid.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MouseModel</span></a> <a href="https://sigmoid.social/tags/DeepImaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DeepImaging</span></a> <a href="https://sigmoid.social/tags/preprintalert" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>preprintalert</span></a> <a href="https://sigmoid.social/tags/DZNE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DZNE</span></a> <span class="h-card" translate="no"><a href="https://social.bund.de/@dzne" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>dzne</span></a></span></p>
Daniel Caron<p>Macrophages are essential immune cells that reside in all tissues. Some macrophages arise from monocytes in the blood, but during fetal development they also come from a unique pathway!</p><p>We still have a lot to learn, but here I'll describe how Zhao et al. (2023) used mouse models to uncover hints about which progenitor cells create tissue-macrophages.</p><p><a href="https://doi.org/10.1016/j.celrep.2023.113364" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.celrep.2023.</span><span class="invisible">113364</span></a></p><p><a href="https://genomic.social/tags/Macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Macrophages</span></a> <a href="https://genomic.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MouseModel</span></a> <a href="https://genomic.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Immunology</span></a> <a href="https://genomic.social/tags/Immunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Immunity</span></a> <a href="https://genomic.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scRNAseq</span></a> <a href="https://genomic.social/tags/FlowCytometry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FlowCytometry</span></a> <a href="https://genomic.social/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Research</span></a> <a href="https://genomic.social/tags/JournalArticle" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JournalArticle</span></a> <a href="https://genomic.social/tags/JournalClub" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JournalClub</span></a></p><p>1/9🧵</p>
Les Sutton<p>Hi <a href="https://fediscience.org/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ScienceMastodon</span></a> - my lab's most recent findings just hit preprint here: <a href="https://www.sciencedirect.com/science/article/pii/S0022202X22018887?via%3Dihub" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sciencedirect.com/science/arti</span><span class="invisible">cle/pii/S0022202X22018887?via%3Dihub</span></a></p><p>We discovered a <a href="https://fediscience.org/tags/mousemodel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mousemodel</span></a> for examining <a href="https://fediscience.org/tags/cSCC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cSCC</span></a> where <a href="https://fediscience.org/tags/mice" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mice</span></a> with epidermal deficiency of <a href="https://fediscience.org/tags/KDM6A" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>KDM6A</span></a> and <a href="https://fediscience.org/tags/P53" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>P53</span></a> show 100% penetrant, spontaneous cSCC development within a year!</p><p><a href="https://fediscience.org/tags/dermatology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dermatology</span></a> and <a href="https://fediscience.org/tags/skincancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>skincancer</span></a> have very few models to study cSCC in mice and our lab found one!</p><p><a href="https://fediscience.org/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> <a href="https://fediscience.org/tags/epigenetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>epigenetics</span></a> <a href="https://fediscience.org/tags/academicchatter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>academicchatter</span></a> <a href="https://fediscience.org/tags/derm" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>derm</span></a> <a href="https://fediscience.org/tags/tumorsuppressors" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumorsuppressors</span></a> <a href="https://fediscience.org/tags/tumor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumor</span></a> <a href="https://fediscience.org/tags/scicomm" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scicomm</span></a></p>