Gregory MS<p><a href="https://gregory-ms.com/articles/300305/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300305" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300305</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300305</span></a></p><p>Myelination RegulAting oligodendrocyte associated LncRNA (MYRACL) is a regulator of functional maturation and oligodentrocytic myelination in human brain tissue. It is non-coding and conserved across species.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
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#MultipleSclerosis
41 posts · 7 participants · 0 posts today
Gregory MS<p><a href="https://gregory-ms.com/articles/300309/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300309" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300309</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300309</span></a></p><p>There are no effective therapeutic options to promote the recovery of motor function following spinal cord injury (SCI). Ketogenic diet (KD) and quercetin (Que) were used to treat SCI in rats. The combined treatment significantly decreased cavity volume, reduced glial scarring and attenuated local inflammatory infiltration.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300215/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300215" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300215</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300215</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300232/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300232" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300232</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300232</span></a></p><p>B cells play a critical role in the pathogenesis of autoimmune inflammatory diseases such as multiple sclerosis. Mice with B-cell-specific deletion of CRTH2 exhibit reduced numbers of IL-1β-producing B cells, resulting in amelioration of EAE.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300294/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300294" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300294</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300294</span></a></p><p>Demyelination is the underlying pathological mechanism of trigeminal neuralgia (TN). Ferroptosis has been implicated in neurodegenerative disorders associated with demyelination. The study has clarified the impact of ferroPTosis-induced demyselination in TN and provided a potential strategy for treating TN.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Bruno Amaral<p>The observatory page now loads faster and has a failsafe to make sure we load all <a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> medications, treatments, and topics. <a href="https://gregory-ms.com/observatory/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">gregory-ms.com/observatory/</span><span class="invisible"></span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurology</span></a> <a href="https://mastodon.social/tags/neurosky" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurosky</span></a> @gregory-ms.com</p>
Bruno Amaral<p>You may notice <span class="h-card" translate="no"><a href="https://mastodon.social/@gregory_ms" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>gregory_ms</span></a></span> posting less. This is because I increased the requirements to consider an article as relevant. We use 3 <a href="https://mastodon.social/tags/AI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AI</span></a> models that score each paper from 0 to 1, and now Gregory only posts the ones where the 3 give a score ≥ 0.9 <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/NeuroSky" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NeuroSky</span></a> <a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300220/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300220" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300220</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300220</span></a></p><p>Gas6 is a promising therapy to promote remyelination in people with multiple sclerosis. Global genetic deletion of Gas6 or the Gas6 receptor Tyro3 results in reduced disease severity following induction of experimental immune encephalomyelitis in mice.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300230/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300230" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300230</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300230</span></a></p><p>The study aimed to investigate the effects of cathodal tsDCS on gait function and fatigue in people with MS compared to sham tsDCS. Results showed a significant improvement in the tsDCS group compared to the sham group.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300206/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300206" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300206</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300206</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300209/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300209" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300209</span><span class="invisible">/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_300209</span></a></p><p>Neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are autoimmune central nervous system disorders with poorly understood immune pathways. CD83 plays a crucial role in the development and maintenance of immune tolerance. The study enrolled 231 untreated participants, including 64 with MOGAD, 56 with NMOSD, 47 with MS, and ...</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300120/?utm_source=mastodon&utm_medium=article&utm_content=300120" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300120</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&utm_content=300120</span></a></p><p>AuToDeCRA-2 is a non-commercial, phase IIa, 5-arm, randomised, unblinded, single-centre study. It aims to establish the optimal dose, route of administration and antigen loading of dendritic cells (TolDC) and develop a biomarker profile to demonstrate immunomodulation.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/1469318/?utm_source=mastodon&utm_medium=article&term=1469318" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/146931</span><span class="invisible">8/?utm_source=mastodon&utm_medium=article&term=1469318</span></a></p><p>SARS-CoV-2 is a virus that causes neurological symptoms. Cells and a 3D blood–brain barrier model were infected with the wild-type form of SARS- cov-2, Alpha, Beta, Delta, Eta, or Omicron variants at various MOI. All variants, except Beta, modulate extracellular glutamate concentration, which can lead to excitotoxicity or altered neurotransmission.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300090/?utm_source=mastodon&utm_medium=article&term=300090" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300090</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=300090</span></a></p><p>Systemic AutoInflammatory Diseases (SAIDs), AutoImmune Diseases (AIDs), and Primary Immune Deficiencies (PIDs) were once considered independent, even opposing, conditions. Now they are overlapping diseases with shared immune system dysfunctions.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300020/?utm_source=mastodon&utm_medium=article&term=300020" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300020</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=300020</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300022/?utm_source=mastodon&utm_medium=article&term=300022" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300022</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=300022</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300046/?utm_source=mastodon&utm_medium=article&term=300046" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300046</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=300046</span></a></p><p>Spinal cord injury (SCI) is one of the long-term neurological deficits with primary and secondary damages. Various treatment strategies have not been successful in SCI treatment. This study designed a platform containing a scaffold, an anti-inflammatory nanostructured drug, and stem cells. The platform was tested in a female Wistar rat model with spinal cord injury. It improved the recovery of ...</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/299976/?utm_source=mastodon&utm_medium=article&term=299976" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/299976</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=299976</span></a></p><p>Lipid metabolism is central to host defense by supporting and modulating immune cell function. Neurodegenerative diseases are genetically linked to disruptions in lipid metabolism. Deciphering this complex cross talk may provide opportunities for novel therapies targeting neuroinflammatory and neurodegenerational disorders.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/299985/?utm_source=mastodon&utm_medium=article&term=299985" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/299985</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=299985</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/300001/?utm_source=mastodon&utm_medium=article&term=300001" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/300001</span><span class="invisible">/?utm_source=mastodon&utm_medium=article&term=300001</span></a></p><p>Corticosteroids and maintenance immunotherapy with rituximab or intravenous immunoglobulin independently lower relapse risk in MOGAD.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
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