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#nitricoxide

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“Conservative estimates from studies of twins and siblings indicate that genetic factors may account for about 80 percent of autism risk. That leaves room for environmental factors. For instance, there are studies suggesting a link between autism and exposure of expecting mothers to #nitricoxide found in air pollution.”

@inkican

Interesting, but the article is frustratingly vague about the mechanism of action.

The drug/MoA is probably the same as in this article⬇️
"PnPP-19 potentiates erection, in vivo and ex vivo, via NO/cGMP pathway, does not affect sodium channels or rat heart, and shows no toxicity and low immunogenicity, what makes it a very promising candidate as a novel drug in the therapy of erectile dysfunction."

dx.doi.org/10.1016/j.juro.2015

~
NO is antimicrobial and it's possible this drug could be used for other purposes.