@SteveThompson
Nice skeptic article as any true science should be. Anything that links the 2011 Russo paper "Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects" is to be celebrated. Here is the link again in case somebody missed it.
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01238.x
Russo's paper has been cited 1,161 times and it deals with exogenous cannabinoids and terpenes synergy, not just endogenous o made inside our body, as did the original 1998 Mechoulam research.
Indeed, due to obsolete prohibitionism and sad profit-comes-first mentality, the current cannabis and hemp markets are a wild west of fake adultered product and unproven claims.
Yet since 2011 hundreds of studies have confirmed the entourage effect. Here is a small and incomplete collection of full spectrum extract papers 2004-2023.
https://www.cvresearch.info/full-spectrum-hemp-extracts-studies
OPs article calls for more standarized extract testing, even though Big Pharmas really prefers patentable, cheap to make, single molecule, symptom masking drugs. Good luck with that.
I agree with the article bottomline: governments should step up to the research task instead of trusting this critical matter to profit-driven corporations. Mixed isolate cannabis pharmaceuticals have been in the market for over a decade and proven their capabilities and limitations.
That is the case of Sativex, a 700 US$ 1:1 (thc:cbd) oral spray that controls some symptoms of MS yet fails to work for other conditions. Three separate studies ( Israeli, Brazilian and American) have since proven that full flower artisanal extracts are up to 6x more effective than expensive isolate preparations like Sativex
https://sensiseeds-com.translate.goog/es/blog/sativex-el-pionero-de-los-farmacos-derivados-del-cannabis/?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=es-419&_x_tr_pto=wapp
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