Today's little book haul Good stuff!
#books
#bookstodon
#dopaminenation
#dopamine
#RebelCode
@glynmoody
#ingloriousempire
#ShashiTharoor
Postdoc available in Iris Hardege in Cambridge University, UK:
On dopamine receptors in C. elegans:
https://www.cam.ac.uk/jobs/research-associate-neuroscience-research-group-fixed-term-pf47153
Impulsive-hyper ADHD overdrive
A lot has happened in the last 2½ months, give or take a few days. Several surgeries, big painful trauma, a great loss causing huge grief… Dealing with all this, and trying to recover of it all, has been taking a lot of me. When you’re already dealing with a chronic illness, you have less spoons to deal with. And then, at some point, you’ve used all available spoons. You’ve used all the spoons that you tried to borrow from days in your future (if that makes sense). You are sad, close to depression, and tying to find a way to prevent that from happening.
My ADHD knows that there is something that gives me “easy dopamine”, a quick rush, a feeling of accomplishment, a short moment of happiness, of satisfying some long-craving needs… Unfortunately, it usually means that my bank account is suffering, and in the end, I am in trouble. I need to recognize it, to realize it, to acknowledge it and then… Fight it. And while I know I can do it, as I’ve done it before, I also know that during times like these, I am not always strong enough to overcome it fast enough.
[…]
https://cynnisblog.wordpress.com/2025/09/06/impulsive-hyper-adhd-overdrive-%e2%98%a2%ef%b8%8f/
Crossing the Blood Brain Barrier
"Reprocessing Episodic Memory", an addition to Project Restoration, and how I've been spending free time thinking about the brain.
> ... blasting the prefrontal cortex with supra-physiological dopamine levels ... blunt-force impact trauma ... boosting its metabolic precursor l-3,4-dihydroxyphenylalanine ...
- https://prose.winterschon.com/reprocessing-episodic-memory/
Found some more, might become a thread if I keep rabbit-holing. I like the "menu" idea, the list of easy go to activities, in this one. Making an actual paper and colored pencil list might be helpful for me.
@overholt Ah, you are ALSO a task management connosseur.
I make #lists.
I obsessively curate my lists.
I even wrote my own list making tool because I got sick of all the existing ones (and fck Trello that's why)
Putting things on lists doesn't actually make them #DONE; they sit there taunting me. However the effort of curating my lists gives me just enough #dopamine to dust my hands going "mission accomplished".
_Uh, you gonna DO any of those?_
Pff. No, those lists are for _show_.
Answering a question from @Andrewpapale. https://fediscience.org/@Andrewpapale/114942272799323905
Yep! Dip in #dopamine happens at the moment of #regret, when the mouse realizes that it made a mistake of its own agency.
And looks different in mice that eventually learn to avoid the wait zone by deliberating in the offer zone (precommitment).
If I can find a video, tv show or music videos, including fan edits, to watch then that solves it. Brain occupied, #dopamine boosted. Posting to the actor blog helps too. Tumblr in general, also here and instagram, depending on my mood. Tumblr is fun for discovery. I haven’t read any #Batman #comics but #Batfam posts come onto my dashboard and they’re great fun. Batman, Superman, the kids and Alfred. I’m a bit lacking in context and quite who’s who, but I love to see it.
@elduvelle_neuro @Andrewpapale
@BrianMSweis
As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.
Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.
"A temporally restricted function of the dopamine receptor Dop1R2 during memory formation", Kaldun et al. 2025 (Sprecher lab).
https://elifesciences.org/articles/99368
In Kenyon cells, "loss of dop1R2 from ab or a'b' block the ability of flies to display measurable forms of longer forms of memory"
In other words, a specific dopamine receptor is now associated with long-term memory in fruit flies, and its loss does not affect short-term memory.
I am currently eating a lot of times out of boredom. I know I am #dopamine seeking but I don’t know how to stop it. Any tips are welcome! I am AuDHD, chronically ill and low energy. No retail therapy please That’s a whole different can of worms #actuallyautistic #ADHD
Position available: Post Doctoral Research Associate in Whole Organism Neuroscience – lab of Iris Hardege, University of Cambridge, UK.
Deadline for application: August 3rd, 2025.
"This BBSRC-funded project aims to understand the interplay between excitatory and inhibitory metabotropic and ionotropic dopamine receptors and how they contribute to the regulation of complex behaviours."
https://www.europesays.com/uk/229784/ This parasite can alter your behavior, and 2 billion humans already have it #behavior #Benchmarks #Dopamine #GraphicsCard #Health #humans #ImmuneSystem #Infection #laptop #MentalDisorders #netbook #neuropsychiatric #notebook #Parasite #processor #reports #Research #Review #Reviews #test #tests #ToxoplasmaGondii #UK #UnitedKingdom
https://www.europesays.com/uk/224852/ Do omega-3 supplements boost athletic performance? #AntiInflammatory #Antioxidant #brain #Cardiometabolic #Cell #cholesterol #Dopamine #exercise #FattyAcids #fish #FishOil #Health #HealthyLifestyle #Inflammation #Lipoprotein #Membrane #metabolism #muscle #Nerve #Nutrients #Nutrition #Omega3FattyAcid #OxidativeStress #Research #serotonin #Stress #supplements #UK #UnitedKingdom
https://www.europesays.com/us/24660/ Do omega-3 supplements boost athletic performance? #AntiInflammatory #Antioxidant #brain #Cardiometabolic #Cell #Cholesterol #dopamine #exercise #FattyAcids #fish #FishOil #Health #HealthyLifestyle #inflammation #Lipoprotein #Membrane #metabolism #muscle #Nerve #Nutrients #Nutrition #Omega3FattyAcid #OxidativeStress #research #Serotonin #stress #supplements #UnitedStates #UnitedStates #US
So prone to this - especially on the job where there's limited distractions and a vending machine nearby!
#Stress eating doesn't always mean craving more: What to know to avoid #overeating https://buff.ly/lMq2R4F