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#sleep

4 posts4 participants0 posts today
Public
Dave Rahardja 26

Sometimes I’m made painfully aware that the world is mostly optimized for early risers. I’m a #nightOwl and like to wake up later in the day, but I’m often forced to wake up earlier to accommodate appointments or other business.

Doing this ruins my sleep cycle and often causes sleep depravation that I then have to recover from over the next three to four days. But often I just have NO CHOICE, because EARLY is just how it’s done in this society.

#sleep
Public
Gretchen K Deahl
The Girl and the Bear
In the quiet forest, walks a gentle bear. Upon his sunny back a young girl sleeps.

This artwork is NOW AVAILABLE in my Redbubble shop:
https://www.redbubble.com/people/gretchenkdeahl/shop
(100% human-made) human imagined, drawn and painted, no AI whatsoever.

#art #artist #illustration #illustrator #spiritual #drawing #paintings #noAI #childrensbooks #fineart #artwork #landscape #nature #childrensart #artforchildren #interiordecor #flowers #mastoart #art #artistsonmastodon #artlover #artlovers #decor #popart #artnet #artlover #artlovers #handmade #supportthearts #monsters #monster #creature #friend #love #march #forest #magic #imagination #fantasyart #fantasy #bear #girl #sleep #de_artists #mastoart #de_artist #artist_de #mastoart #mastoartist #de_artists
Early in the morning, at the edge of a forest of brown and purple, greens and gold, a smiling bear pads quietly across the grass. Caught in a sunbeam, a young girl in a flowered yellow dress is sleeping upon his back, her arms folded under her head. Plants, like ferns and budding flowers, line each side of the glade. NOTE: This description is created especially for my lovely blind friend, Georgiana. :-)
Public *
JADe (he, him)

"A bias against cannabis still exists today. While the roots of weed prohibition have many unfortunate layers, storytelling played a huge role in negative public opinion around the plant. Some publications continue to feed into the modern version of “Reefer Madness,” what I call Reefer Madness 2.0. One article from a respected legacy publication just last year centered on how to get your neighbor evicted for smelling like weed. Not only is this type of storytelling cruel and inhumane (what if they are a medical patient, or a child with epilepsy?), most importantly, it’s not based on science."

Nice sunday read. The article goes on to propose to 1. Reframe Weed As Wellness, 2. Lean On Peer-Review Studies and 3. Dare To Question Existing Tech Platforms (and censorship). It advocates for invite-only discord grow diaries, yet fails to mention the #fediverse and #mastodon as great tools to keep #freedomofexpression and #humanrights going.

Lets get that corrected. Help me share this and let Rolling Stone know about our existence.

rollingstone.com/culture-counc

#medical #cannabismedicinal
#marijuana #weed #thc #thca #cbd
#Cannabisgesetz #cannabislegal
#marihuana #maconha #pain #ganja
#adhd #depression #sleep #stress #hemp #healthcare #nervepain
#righttorepair #pot #health
#Stoner #cannabismedicine #ChronicFatigueSyndrome #arthritis
#epilepsy #cancer #Lupus

Stock Adobe
Rolling Stone · Debunking Cannabis Myths: 3 Ways To Change the NarrativeBy Lindsey Bartlett
Public
Gretchen K Deahl
The Girl and the Bear
In the quiet forest, walks a gentle bear. Upon his sunny back a young girl sleeps.

This artwork is NOW AVAILABLE in my Redbubble shop:
https://www.redbubble.com/people/gretchenkdeahl/shop
(100% human-made) human imagined, drawn and painted, no AI whatsoever.

#art #artist #illustration #illustrator #spiritual #drawing #paintings #noAI #childrensbooks #fineart #artwork #landscape #nature #childrensart #artforchildren #interiordecor #flowers #mastoart #art #artistsonmastodon #artlover #artlovers #decor #popart #artnet #artlover #artlovers #handmade #supportthearts #monsters #monster #creature #friend #love #march #forest #magic #imagination #fantasyart #fantasy #bear #girl #sleep #de_artists #mastoart #de_artist #artist_de #mastoart #mastoartist #de_artists
Early in the morning, at the edge of a forest of brown and purple, greens and gold, a smiling bear pads quietly across the grass. Caught in a sunbeam, a young girl in a flowered yellow dress is sleeping upon his back, her arms folded under her head. Plants, like ferns and budding flowers, line each side of the glade. NOTE: This description is created especially for my lovely blind friend, Georgiana. :-)
Public
flypapers

📰 "Identification of new KCNT1-epilepsy drugs by in silico, cell and Drosophila modelling."
biorxiv.org/content/10.1101/20
#Drosophila #Sleep

bioRxiv · Identification of new KCNT1-epilepsy drugs by in silico, cell and Drosophila modellingObjective Hyperactive KCNT1 potassium channels, caused by gain-of-function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug-resistant seizures and in cases with infantile onset, developmental regression can follow. KCNT1-related disorders include epilepsy of infancy with migrating focal seizures and sleep related hypermotor epilepsy. There are currently no effective treatments for KCNT1-epilepsies, but suppressing over-active channels poses a potential strategy. Methods Using KCNT1 channel structural data, we in silico screened a library of known drugs for those predicted to block the channel pore to reduce the current amplitude and inhibit channel activity. Results Eight known drugs were investigated in vitro for their effects on patient-specific mutant KCNT1 channels, with four drugs showing significant reduction of K+ current amplitudes. The action of the four drugs was then analyzed in vivo and two were found to reduce the seizure phenotype in humanized Drosophila KCNT1-epilepsy models. Interpretation This study identified two known drugs, antrafenine and nelfinavir mesylate, that reduce KCNT1 channel activity and reduce seizure activity in whole animals, suggesting their potential use as new treatments for KCNT1-epilepsy. The sequential in silico , in vitro and in vivo mechanism-based drug selection strategy used here may have broader application for other human disorders where a disease mechanism has been identified. ### Competing Interest Statement The authors have declared no competing interest. BBSRC, BB/M011151/1 Channel 7 Children’s Research Foundation Grant National and Health Medical Research Council of Australia, 1104718, 1125523, 2028987
Public
Swede’s Photographs

Good morning. 😴🥱💤

27 May 2025

I woke just after three this morning to the rumble of a passing thunderstorm. Knowing dogs don’t care much for storms, I opened the bedroom door and let Charlie in. As tired as I was, sleep wasn’t an option, so I abandoned the idea and made my way to the recliner—only to find that wasn’t working either. Might as well brew a pot of coffee.

While going through the motions, I realized we were running on generator power again—second time in two days. That reminds me, I’ll need to check the fuel level later this morning, along with the oil, since it’s been working overtime. But for now, I think I’ll give the recliner one more shot.

"Life isn't about waiting for the storm to pass. It's about learning to dance in the rain." – Vivian Greene

Dance of the Skimmers "This striking image captures a flock of black skimmers gracefully soaring through the sky, their wings outstretched in various positions. The birds move in harmony, creating a sense of fluidity and elegance. The backdrop of the sky, blending soft blue and orange tones, adds warmth and depth to the scene. This composition beautifully highlights the unique flight patterns and wing shapes of black skimmers, showcasing their natural behavior in motion." - Copilot
#photo#photography#photographer
Public
Cynni's Blog

Tired…

...of being (so very) tired... I've been struggling with my health for a bit. Arwen has been struggling with hers too. It makes me more stressed. I can't do the things that I love to do. I can't exercise as I'd like. I can't sleep properly anymore. I get some good sleep, usually, but if it's 6 hours, then that's it. And if I try to keep more, I am often rewarded with freakingly bad nightmares, so I just get up when I am awake. But, it leaves me more and more tired. And while I would like to keep going, it's getting harder to do so every day... And, when I have the time to relax a bit, with a movie on the couch, after some walkies with Arwen... I usually almost start to doze off... And then my brain remembers that I should do something first, before I an relax. And once I have done that, it will be impossible for me to snooze... I will try, and I will fail. And well, to be honest, I am just so tired of feeling tired all the time. And I am annoyed that my body and brain won't allow me the time I need to relax and recharge... […]

cynnisblog.wordpress.com/2025/

An anime-style character with rainbow-colored hair, blue glasses, and sparkly rainbow fairy wings, wearing a purple hoodie. They look sad and tired, sitting next to a brown dog with a concerned expression. The background is textured gray with a rough, black-and-white border. Text across the image reads, 'Tired... ...of being tired...' in bright pink and blue lettering.
#exhausted#health#limitedenergy
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