The claim is circulating that antidepressants can cause overheating and dehydration. This is a genuine public health message, but it's not so simple: diuretics, beta blockers, ACE inhibitors, antipsychotics, and some antihistamines may also interact badly with hot weather.
https://www.nytimes.com/2024/06/15/well/live/heat-weather-medication-safety.html (excerpt in a reply)

There's even doubt about antidepressants having this effect. A recent paper in eClinicalMedicine looked at all the studies they could find and concluded that there wasn't evidence of antidepressants causing overheating in hot weather - though some other medicines do.

"Current evidence supports strong anticholinergics, non-selective beta-blockers, adrenaline, and anti-Parkinson’s agents impairing thermoregulation during heat stress ... physicians should interpret with caution conventional public health messaging related to the thermoregulatory effects of some drugs (e.g., antidepressants) during hot weather."
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00465-6/fulltext

Given my earlier work on the reporting of harms https://www.researchgate.net/profile/Tom-Kindlon/research I was informed of an upcoming special issue of Trials on assessing #harms in clinical trials, "The collection, analysis and reporting of adverse events in randomised controlled trials"

https://www.biomedcentral.com/collections/CART

These days I focus on @IrishMECFSAssociation but perhaps of interest to somebody. With all the exercise and other #LongCovid trials, it remains important