Your govt at work:Paxlovid Medicare with Medigap Insurance: $263. With GoodRX: $1,500. Before the Covid crisis was declared over: Nil. Feels like they'd just assume we die.

Government efficiency, my ass.

· People with recent COVID-19 at higher risk for other viral and bacterial infections
· A 15-day course of #Paxlovid did not “significantly improve health outcomes in participants with #LongCOVID
· 2. study showed that Paxlovid taken within 5 days of infection with COVID-19 did help with the acute phase of COVID-19 in children
· Rapamycin, a drug used for organ transplants, may help alleviate symptoms of myalgic encephalomyelitis #MECFS

https://thesicktimes.org/2025/04/08/research-updates-april-8/

"There are over 200 different symptoms that can appear in any different combination. And then the other piece about it is there are about six different mechanisms of what can be causing long COVID. So everyone has in common COVID as the thing that started their long COVID.

However, there are so many different physiological things going wrong in different people with long COVID, they might require different treatments."

"There are actually a lot of great trials going on [...] one looking at mitochondrial dysfunction is Rapamycin, which David Petrino’s group is running."

"There’s a few looking at immunomodulation with JAK inhibitors, both the Baricitinib trial by Wes Eli’s group and another JAK inhibitor trial that’s starting at Harvard. Another immunomodulation option is IVIG, which is being run by the NIH RECOVER consortium. This one’s tricky because it’s not super scalable. You have to get the antibodies from people and then infuse them into other people"

"And then the other mechanism that’s being looked at a lot now is viral persistence, both through a few different monoclonal antibodies trials– Michael Peluso’s, funded by the Patient Led Research Collaborative. Nancy Klimas is just starting one funded by the Schmidt Initiative for Long COVID and the state of California. And then there’s another one in Italy that’s funded by industry, all looking at monoclonal antibodies. And then the last viral persistence one is also being run by the Petrino group on Truvada, which is an HIV antiviral."

https://www.sciencefriday.com/segments/paxlovid-long-covid/

@patientled

After 5 years of fighting to not get #COVID, wearing masks, not eating indoors, etc. I finally tested positive after my dad’s funeral.

I’ve had every vaccine and booster and so far the symptoms are very mild. 72 hours after exposure:
- Chills; but no fever.
- Body aches
- Slight soar throat
- Little appetite

Not a candidate for #Paxlovid even with #UC since I’m not on an immunotherapy.

I’m hoping it passes quickly.

Omg.

An elderly family member is in the ER for a fall. This person is 83, has Parkinson's Disease, and is a lifelong smoker. While in the ER, they tested positive for covid.

Their caregiver requested #Paxlovid and reports, "The doctor that was here was like we don't prescribe that and it doesn't work. That is exactly what she said."

?!?!

1/2

Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with hospitalizations, deaths, & CV events.
@DavidJoffe64 at X

https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346

Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with hospitalizations, deaths, & CV events.
@DavidJoffe64 at X

https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346

Trying to figure out whether to take #paxlovid for what is I guess a fairly mild case of #covid. Feel like crap, elevated heart rate (like usually resting is 54, now like 85 and over 100 just from standing up). O2 SAT is pretty normal. Temp 99. Had the damn newest vaccine 3 weeks ago

I called my doc and talked to the triage nurse. They could give it to me. But she said it won’t prevent deeper damage to brain and organs and such, just alleviate symptoms. With trade off of metal taste and rebound

Gibt es hier Mediziner*innen? Kann jemand diesen Text verstehen? Entweder es sterben weniger Menschen oder es hat keine Wirkung über den Placebo hinaus. Die einzige Möglichkeit, wie dieser Text wahr sein kann, besteht darin, dass die Tatsache, dass weniger Menschen gestorben sind, auf Placebo-Effekte zurückzuführen war. Aber dann könnten wir auch #Homöopathie betreiben.

https://taz.de/Archiv-Suche/!6040199/

I was wondering why absolutely ZERO pharmacies had #paxlovid the last time I called.

Not only do we have to pay $1,500 for a 5-day course, but it also has to be special ordered - taking multiple days.

Thanks #higgs!

https://www.cbc.ca/news/canada/new-brunswick/paxlovid-new-brunswick-coverage-drug-plans-eligibility-1.7348556

“The clinical and public health community needs to strongly consider and promote COVID-19 treatments to improve patient outcomes and minimize severe COVID-19. Public health officials and health care professionals need to better educate patients and their families about the benefits of treatment relative to the risk of severe COVID-19.
Antiviral treatment for mild to moderate COVID-19 should be started within 5 to 7 days of symptom onset among persons at high risk of severe disease.”
https://jamanetwork.com/journals/jama/fullarticle/2824607

New: Want To Prevent Long Covid? Should You Take Metformin Or Paxlovid? via
@forbes
https://forbes.com/sites/judystone/2024/09/25/want-to-prevent-long-covid-should-you-take-metformin-or-paxlovid/ #LongCovid #Metformin #Paxlovid

Holy smokes! I won’t be leaning on #paxlovid for help this time. That price for a five day supply is INSANE. This treatment happens to just be two generics, BTW.

Thanks, for price gouging, Pfizer!

i just tested positive for covid and need help - is there any way to get paxlovid prescribed in the US without having liver function blood tests? I don't want to have to wait to get those done and for results to come in, and I'm not on any medications that would make me at higher risk for liver failure iirc
#CovidIsNotOver #paxlovid #WearAMask

Update nach fast 24 h #Paxlovid: Es scheint schon zu wirken, wobei eine Besserung natürlich auch ohne hätte eintreten können. Jedenfalls geht es mir endlich etwas besser, und auch der zweite Strich auf dem Test ist deutlich schwächer geworden. Einzige Nebenwirkung bisher: permanenter bitterer Geschmack im Rachen. #CovidIsNotOver

Erste Dosis #Paxlovid geschluckt. Es war erstaunlich unkompliziert, es von meinem neuen Hausarzt verschrieben zu bekommen. Bin gespannt, ob ich Nebenwirkungen bemerke, wobei die ggf. nicht von den #COVID-Symptomen zu unterscheiden wären.

How to get Paxlovid for free--with or without insurance.

#Paxlovid #Paxcess #COVID19 #COVID

Direct archived WaPo reporting:
https://archive.is/gXw4z