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#brain

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#Zoomposium with Dr. #Gabriele #Scheler: “The #language of the #brain - or how #AI can learn from #biological #language #models

There is a #paradigmshift away from the purely information-technological-mechanistic, purely data-driven #Big #Data concept of #LLMs towards increasingly information-biological-polycontextural, structure-driven #artificial, #neural #networks (#KNN) concepts.

More at: philosophies.de/index.php/2024

or: youtu.be/forOGk8k0W8

Was talking memory with a friend recently and mentioned SDAM, Severely Deficient Autobiographical Memory, that they had never heard of. Another poll friends.

With age, almost all humans deal with decline in memory and other #brain functions. But the minds of some people in their 80s and beyond function as though they were decades younger. Scientists have been studying these superagers for 25 years, testing their memory skills and autopsying their brains when they die. Two things stand out: Not all superagers do all the healthy things you might expect, but nearly all of them are highly social. medium.com/wise-well/secrets-o #neuroscience #science

A human brain donated to science by a superager
Wise & Well · Secrets of Remarkable ‘Superager’ Brains Revealed - Wise & Well - MediumBy Robert Roy Britt

Researchers led by Bruce A. Yankner, prof of genetics, neurology at Harvard Medical School reported that they were able to reverse #Alzheimer’s in mice, restore #brain function w small amounts of compound #lithium enough to mimic metal’s natural level in the brain. “The obvious impact is that because lithium orotate is dirt cheap, hopefully we will get rigorous, randomized trials testing this very, very quickly”...msn.com/en-us/science/biochemi #healthcare #medicine #research

www.msn.comMSN

#Alzheimer's Might Not Actually Be a #Brain #Disease, Says Expert
Based on our past 30 years of research, we no longer think of Alzheimer's as primarily a disease of the brain. Rather, we believe that Alzheimer's is principally a disorder of the #immunesystem within the brain.
The immune system, found in every organ in the body, is a collection of cells and molecules that work in harmony to help repair injuries and protect from foreign invaders.
sciencealert.com/alzheimers-mi

ScienceAlert · Alzheimer's Might Not Actually Be a Brain Disease, Says ExpertThe pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies.

Positive Emotion Enhances Memory by Promoting Memory Reinstatement across Repeated Learning

jneurosci.org/cgi/content/shor

Journal of Neuroscience · Positive Emotion Enhances Memory by Promoting Memory Reinstatement across Repeated LearningIn daily life, we frequently encounter items within emotional contexts through repeated exposure. However, it remains unclear how emotion influences the memory of items learned across multiple repetitions and how neural representations during repeated learning are associated with subsequent memory performance. In the current study, participants learned meaningless squiggles, each followed by an emotional image (positive, neutral, or negative), with each squiggle–image pair presented three times during encoding. After a 24 h delay, a recognition memory test for the squiggles was performed. The results indicated that behaviorally squiggles were more accurately retrieved in the positive condition compared with the negative condition. An old/new ERP effect was observed between 400 and 1,200 ms at the midparietal cluster, specific to the positive condition, and correlated with memory performance. Notably, greater EEG representational similarity of neural patterns across repeated learning was observed for subsequently remembered items compared with forgotten items in the positive condition, specifically at the right frontal region between 380 and 600 ms. These findings suggest that positive emotion enhances memory of neutral items across repeated learning through neural representational reinstatement, offering insights into how emotional differences in episodic memory retrieval are linked to neural patterns established during repeated learning.