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#IBD

1 post1 participant0 posts today
RDN

Increased succinate in the food and gut of mice induced symptoms of inflammatory bowel disease. Succinate acts by impairing the effectiveness of T cells that regulate inflammation.

Summary: medicalxpress.com/news/2025-06

Original paper (not open access): nature.com/articles/s41590-025

Medical Xpress · How a common metabolite worsens inflammatory bowel diseaseBy Olivia Dimmer
#Science#Health#IBD
Martin

Hey peeps, got a little time to assist in some research? add your voice.
I've previously completed a survey and have confirmed with James and Melanie that it's OK to share on Mastodon.
Boosts appreciated.

#autoimmune #lupus #flare #IBD #RheumatoidArthritis #mctd #uctd #sjogrens #SystemicSclerosis #PolymyalgiaRheumatica #MultipleSclerosis #ThyroidDisease #AutoimmuneEncephalitis #AntiphospholipidSyndrome #Type1Diabetes

-message-
We’re now conducting a new survey, 'INSPIRE-Flare', to build

Science Updates

This natural compound found in ginger might be a "better option" in IBD treatment than anything currently available since it doesn't interfere with the immune system or liver function, both of which can cause side effects, said Professor Henry Krause, of the University of Toronto.

#ginger #IBD #health #medicine #science #research

labroots.com/trending/cell-and

LabrootsHow a Ginger Compound May Help Relieve IBD | Cell And Molecular BiologyResearchers have identified a compound in ginger that could treat some symotoms of inflammatory bowel disease. | Cell And Molecular Biology
Daryl

Wow!
Linking a particular bacteria of the gut microbiome in a chain that could potentially be a source of major depression. Follow up research could also show how environmental contaminants combined with the metabolism of the gut microbiome could be linked to autoimmune and other conditions.

Science is amazing!
Can't wait to see where this drives other future research and, eventually, treatments.

hms.harvard.edu/news/drawing-l

hms.harvard.edu · Drawing a Line From the Gut Microbiome to Inflammation and DepressionStudy provides explanation for one bacterium’s link to mental health
#crohns#crohnsDisease#IBD
Replied in thread
Daryl

@Mrfunkedude Pretty sure that's held by someone with #IBD. 😂

There was a time during a flare when I visited the toilet 20+ times a day. None of them were ever short visits, either.

Emmanuelle Skaly

I'm not sure how I feel about sharing my mental health and physical disability conditions and info or how much to do it in good taste.

On one hand I'm an extremely straight forward and obsessively honest person. I like sharing because it's genuinely just authentic for me and I also just have nothing to hide. In a way I'm doing it right now.
As well as, it's useful. Speaking up about disabilities can and does inspire others to feel more comfortable and confident about themselves, understanding they're not alone with their difficulties.

On the other hand, the victim card sickens me. I've had enough of being a victim. I've had enough of people feeling sorry for me and of identity based conversations saying that just because I have certain conditions it somehow gives me a greater right for attention or support when in reality so many people have massive difficulties that may not be as clearly diagnosable and still hugely impact their lives and the way they deal with failures and successes.

I am deeply grateful for the many people who have supported me because of my traumas, abuse, physical chronic illnesses and many trauma related mental disabilities. Empathy is powerful and when someone shares the least we can do is listen with open curiosity and kindness.

But if I keep emphasizing how much of a victim I am, I might just be a victim forever. If I keep inviting people to feel sorry for me, I might create a reality in which I'm forever weak. And is it my fault? No. But is it my responsibility to change it? Absofuckinglutely.

I'm already on this path but sometimes I stumble. Sometimes I still use the victim card with myself and others.

The line is thin but critical, between being aware and taking good care of my many disabilities, to letting them disable me completely, or even just, more than they must.

I may forever have times in which I'll suffer from OCD episodes, panic attacks, mental breakdowns and clinical depression. But I'll do my best to limit those symptoms as much as I possibly can and not allow them from avoiding me of a good life.

I will forever have NVLD, but instead of letting it define what I can or can not do, I'll find alternative ways to do and understand anything I need to achieve my goals.

I may forever suffer from IBD and anemia. But I'll do what I can to manage and if I find a way, heal. And as much as possible, as much as healthy, continue my life with those illnesses, and aspire for joy and health as much as anybody else.

I won't beg for government support of any kind, I'll never take a loan ever in my life, I won't depend mentally on loved ones. I know others may have to. I had times in which I had to as well. But as long as I can change my mindset and health to be more capable of full independence, I place my responsibility and focus on doing so.

I'm a fully independent business owner and I am happy. Inconsistently happy, struggling but happy, overly stressed but happy. In love and happy, studying and working what I love and happy. Living a very strange reality impacted by war but happy. And yes, I have illnesses. And yes, I have many disabilities. But as for my identity, I can recognize my illnesses and take care of them, but I am healthy, I am not ill. I can acknowledge and understand my disabilities, I have many differences and many things I can do better than others naturally and many that I am naturally a lot worse at than most people. But I am not disabled. In fact, I'm completely capable of reaching my goals, it just requires different ways which I'm creative enough to figure out.

It's very hard. It's mind shattering sometimes. It's my body crumbling other times. But it's the truth.

So here I give up my victim card in society and in front of myself and consider myself an equally capable human being.

Capable of artistic, financial and wellness growth.

Capable of everything I want, but most importantly - capable of good influence on others through art.

Yours,
Emmanuelle

#disablity#mentalhealth#ocd
𝙘𝙖𝙡𝙖𝙢𝙞𝙩𝙮 𝙞𝙯𝙯𝙮 🌻

FYI pinned post:

in january, I was diagnosed with crohn's disease. my diagnosis came with some nasty complications that I'm still very much dealing with medically. I try to put my medical-related posts behind content warnings, with a note if it involves hospitals, operations, and bodily functions and/or fluids. I also complain a lot in these posts. if I miss a warning, please don't hesitate to let me know, and if medical stuff isn't your thing, I won't be offended if you unfollow, mute, or block me.

I am also trying to follow other folks with IBD, since I'm new to it. I occasionally look at #ibd, #chrohns, and @ibd@a.gup.pe.

​:blobcatcool:​

izzy!!

FYI pinned post:

in january, I was diagnosed with crohn's disease. my diagnosis came with some nasty complications that I'm still very much dealing with medically. I try to put my medical-related posts behind content warnings, with a note if it involves hospitals, operations, and bodily functions and/or fluids. I also complain a lot in these posts. if I miss a warning, please don't hesitate to let me know, and if medical stuff isn't your thing, I won't be offended if you unfollow, mute, or block me.

I am also trying to follow other folks with IBD, since I'm new to it. I occasionally look at #ibd, #chrohns, and @ibd@a.gup.pe.

​:blobcatcool:​

Science Updates

"Using genetics as a starting point, we've uncovered a pathway that appears to play a major role in IBD and other inflammatory diseases. Excitingly, we've shown that this can be targeted therapeutically, and we're now working on how to ensure this approach is safe and effective for treating people in the future," said Dr James Lee.

#IBD #biology #research #health #medicine #gastroenterology #science

labroots.com/trending/genetics

LabrootsA Major Cause of Inflammatory Bowel Disease is Revealed | Genetics And GenomicsIn inflammatory bowel disease (IBD) https://www.cdc.gov/ibd/what-is-ibd.htm , the gastrointestinal (GI) tract is chronically inflamed, and the term may ref | Genetics And Genomics
Auscandoc

bbc.com/news/articles/c1wwdd6v “The group of researchers at the Francis Crick Institute and University College London performed a deep genetic analysis to try to unpick the cause of the #IBD.
They discovered a section of genetic code – or #DNA – that turns out to be the #macrophage’s “master regulator” of #inflammation.
It sits right at “the top of the pyramid” says Dr James Lee, from the Francis Crick Institute. (1/2)

www.bbc.comMajor cause of inflammatory bowel disease foundScientists have found a weak spot in our DNA that is present in 95% of people with the disease.
Rhyothemis

Irritable [sic]* Bowel Disease cases surging in children and adults
youtu.be/KrS79dRhWik?si=mgjmxO

* they mean Inflammatory Bowel Diseases, i.e, Chron's disease and ulcerative colitis

The graph at 2:30 is alarming. I tried to find the source document on the Chron's and Colitis Foundation website, but was unable.

Here's a related article on pediatric IBD in Canada showing the same uptick -

New study links air pollution to cases of inflammatory bowel disease in B.C. children
cbc.ca/news/canada/british-col

#health #medicine #gastroenterology #environment #AirPollution
#IBD #InflammatoryBowelDisease #Chrons #UlcerativeColitis

YouTubeIrritable Bowel Disease cases surging in children and adultsBy CBS Colorado
TrendingLive feeds
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